Colitis
|
0.570 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, ZFE effectively modulated the mRNA expression of redox-sensitive transcription factors, such as nuclear factor (erythroid-derived 2)-like 2 and heme oxygenase-1, downregulated the expression of p38 mitogen-activated protein kinase, and upregulated that of vascular endothelial growth factor A and interleukin-1β in AcOH-induced colitis in rats.
|
29518435 |
2018 |
Colitis
|
0.570 |
AlteredExpression
|
disease |
BEFREE |
Our data indicate that ESG, digested with α-amylase to RG, suppresses DSS- and TNBS-induced colitis by increasing the expression of HO-1 in the large intestine of mice.
|
28257879 |
2017 |
Colitis
|
0.570 |
Biomarker
|
disease |
BEFREE |
This study was undertaken to elucidate the Bach1/HO-1 system's effects on the pathogenesis of experimental colitis.
|
23446334 |
2013 |
Colitis
|
0.570 |
Biomarker
|
disease |
BEFREE |
In this study, we found that increased expression of Mkp-1, Nrf2, and heme oxygenase 1 (Ho-1) was correlated in colonic tissues in patients with ulcerative colitis and Crohn's disease, as well as wild-type mice with colitis induced by dextran sodium sulfate (DSS).
|
30061089 |
2018 |
Colitis
|
0.570 |
Biomarker
|
disease |
BEFREE |
15-Deoxy-Δ<sup>12,14</sup>-prostaglandin J<sub>2</sub> ameliorates dextran sulfate sodium-induced colitis in mice through heme oxygenase-1 induction.
|
31704099 |
2019 |
Colitis
|
0.570 |
AlteredExpression
|
disease |
BEFREE |
PHB Tg/Nrf2(-/-) mice mimicked PHB Tg mice, with attenuated DSS- or TNBS-induced colitis and induction of colonic HO-1 and NQO-1 expression, despite deletion of Nrf2.
|
23494124 |
2013 |
Colitis
|
0.570 |
AlteredExpression
|
disease |
BEFREE |
We also found that treatment with AcEGCG increased heme oxygenase-1(HO-1) expression via activation of extracellular signal-regulated protein kinase (ERK)1/2 signaling and acetylation of NF-E2-related factor 2 (Nrf2), thereby abating DSS-induced colitis.
|
22409325 |
2012 |
Colitis
|
0.570 |
Therapeutic
|
disease |
CTD_human |
An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis.
|
21444764 |
2011 |
Colitis
|
0.570 |
Therapeutic
|
disease |
CTD_human |
Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway.
|
16365149 |
2005 |
Colitis
|
0.570 |
Therapeutic
|
disease |
RGD |
BTZO-15, an ARE-activator, ameliorates DSS- and TNBS-induced colitis in rats.
|
21853095 |
2011 |
Colitis
|
0.570 |
Biomarker
|
disease |
RGD |
A vegetal ALA-rich formula decreases the expression of ICAM-1, VCAM-1, and VEGFR-2 and independently of HO-1 in rats with TNBS-induced colitis.
|
22261574 |
2012 |