Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
For comparison, HO-1 levels were assayed in RPE cells from four donor eyes with long-standing hypertension.
|
9134328 |
1997 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
RGD |
Selective regulation of blood pressure by heme oxygenase-1 in hypertension.
|
12215473 |
2002 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
The AA genotype of HMOX-1 is associated with an increased incidence of hypertension in women.
|
12872043 |
2003 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
LHGDN |
The AA genotype of HMOX-1 is associated with an increased incidence of hypertension in women.
|
12872043 |
2003 |
Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
This study evaluated in 16 pediatric renal transplant patients, divided in two groups based on the presence of post-transplant hypertension, the oxidative stress status measuring the gene expression (reverse transcription-polymerase chain reaction) of two major oxidative stress-related proteins, p22(phox) and heme oxygenase-1 (HO-1).
|
16860128 |
2006 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
CTD_human |
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects.
|
16959961 |
2006 |
Hypertensive disease
|
0.600 |
Therapeutic
|
group |
CTD_human |
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects.
|
16959961 |
2006 |
Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
In this work, we have addressed whether expression of heme oxygenase-1 (HO-1), an antioxidant enzyme, becomes altered in these cells upon Ang II treatment or under hypertension conditions.
|
18515325 |
2008 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
On balance, however, the strategies to target heme oxygenase-1 as described in this review offer promising therapeutic approaches to clinicians for the effective management of hypertension and renal function.
|
19027871 |
2009 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
The multifactor-dimensionality reduction analyses results did not show any interaction between the HMOX1 and HMOX2 genes underlying the development of hypertension.
|
19886851 |
2009 |
Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension.
|
20957739 |
2011 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Study on the association between environmental cadmium exposure, cytochrome P450-mediated 20-HETE, heme-oxygenase-1 polymorphism and hypertension in Thai population residing in a malaria endemic areas with cadmium pollution.
|
21787712 |
2011 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
CTD_human |
Overexpression of HIF-1α transgene in the renal medulla attenuated salt sensitive hypertension in Dahl S rats.
|
22349312 |
2012 |
Hypertensive disease
|
0.600 |
Therapeutic
|
group |
CTD_human |
Overexpression of HIF-1α transgene in the renal medulla attenuated salt sensitive hypertension in Dahl S rats.
|
22349312 |
2012 |
Hypertensive disease
|
0.600 |
Therapeutic
|
group |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
Heme oxygenase-1 induces 15-lipoxygenase expression during hypoxia-induced pulmonary hypertension.
|
23391748 |
2013 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
The impaired D5R regulation of HO-1 and ROS production contributes to the pathogenesis of hypertension in D5(-/-) mice.
|
23425954 |
2013 |
Hypertensive disease
|
0.600 |
Biomarker
|
group |
BEFREE |
We recently demonstrated that heme oxygenase-1 (HO-1) protects against hypertension in a rat model of placental ischemia; however, whether HO-1 regulation of β-ENaC contributes to the beneficial effects of HO-1 is unknown.
|
24553299 |
2014 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
HMOX1 rs743811 associated with chronic kidney disease stage (OR=3.0, P=0.0001) in the University of Illinois cohort and end-stage renal disease (OR=10.0, P=0.0003) in the Walk-Treatment of Pulmonary Hypertension and Sickle cell Disease with Sildenafil Therapy cohort.
|
26206798 |
2015 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Regarding to the (GT)n repeats, the LL genotype showed a higher odds ratio for the development of albuminuria only in patients with hypertension when compared to the S allele.In conclusion, the T(-413)A SNP in the HO-1 promoter is significantly associated with albuminuria development in type 2 diabetes patients, especially with longer duration and poor glycemic control.
|
26512585 |
2015 |
Hypertensive disease
|
0.600 |
GeneticVariation
|
group |
BEFREE |
Finally, individuals with unfavourable HMOX1 gene promoter length had increased prevalence of arterial hypertension and reduced cumulative survival after a median follow-up of 7.23 years.
|
26516175 |
2015 |
Hypertensive disease
|
0.600 |
AlteredExpression
|
group |
BEFREE |
The aim of the present study was to explore the mechanisms of depression and hypertension by examining the expression and interaction of renin/prorenin receptor (PRR) and heme oxygenase 1 (HO-1) in vascular endothelial cells.
|
31410134 |
2019 |