HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Disease: Anemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia 		0.020 AlteredExpression disease BEFREE Homozygous heme oxygenase 1 deletion in mice leads to a paradoxical accumulation of nonheme iron in macrophages, hepatocytes, and many other cells and is associated with low plasma iron levels, anemia, endothelial cell damage, and decreased resistance to oxidative stress. 12382200 2002
CUI: C0002871
Disease: Anemia
Anemia 		0.020 Biomarker disease BEFREE Growth retardation, anemia, iron deposition, and vulnerability to stressful injury are all characteristics observed in recently described HO-1 targeted mice. 9884342 1999