|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
It was also reported that HO-1 induction improved the cardiac function and postinfarction survival in animal models of heart failure or myocardial infarction.
|
31344980 |
2019 |
|
Myocardial Infarction
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction.
|
31080351 |
2019 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
In addition, the associated mechanism involved in these processes was examined in an MI model, and particularly focused on the nuclear factor erythroid 2-related factor (NRF2)/heme oxygenase-1 (HO-1) pathway.
|
31228798 |
2019 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Echocardiography was employed to detect the effect of HO-1 on heart function in adult mice with myocardial infarction (MI) and aged mice.
|
30527623 |
2019 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
To investigate the correlation between three-dimensional echocardiography and the expressions of hypoxia-inducible factor-1 alpha (HIF-1α), heme oxygenase 1 (HO-1) and vascular endothelial growth factor (VEGF) in patients with myocardial infarction.
|
29771427 |
2018 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Significantly lower incidence of left ventricle (LV) free wall rupture was noted between 3rd and 5th day after MI in Hmox1<sup>-/-</sup> mice resulting in their better overall survival.
|
28534119 |
2017 |
|
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The HO-1 risk polymorphism was more frequent in patients post-myocardial infarction (61.3% vs 32%; P=.0097), or with diabetes (68.4% vs 35.5%; P=.011) or a higher FRS (21.5 vs 15.7; P=.014).
|
23293173 |
2013 |
|
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
In this study, rabbits were treated with ADSCs transduced with HO-1 (HO-1-ADSCs), treated with non-transduced ADSCs, or injected with phosphate buffered saline 14 days after experimental myocardial infarction was induced, when autologous ADSCs were obtained simultaneously.
|
22450704 |
2012 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Akt and HO-1 enhance late outgrowth EPC neovascularization, resulting in improved cardiac performance and reduced negative remodeling after myocardial infarction in nude mice.
|
22776314 |
2012 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
RGD |
Our current findings support the premise that HO-1 transduced by MSCs can induce angiogenic effects and improve heart function after acute myocardial infarction.
|
20925964 |
2010 |
|
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
A (GT)n dinucleotide repeat and a -413A>T single nucleotide polymorphism have been reported in the promoter region of HMOX1 to both influence the occurrence of coronary artery disease and myocardial infarction.
|
19389234 |
2009 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
We assessed the effect of HO-1 gene delivery on long-term survival, myocardial function, and left ventricular (LV) remodeling 1 yr after myocardial infarction (MI) using echocardiographic imaging, pressure-volume (PV) analysis, and histomorphometric approaches.
|
17322421 |
2007 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
Our data indicate that rAAV-HO-1 gene transfer markedly reduces fibrosis and ventricular remodeling and restores LV function and chamber dimensions after myocardial infarction.
|
16449792 |
2006 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
In a mouse model for myocardial infarction, the vigilant vectors turned on therapeutic genes such as heme oxygenase-1 in response to ischemia, significantly reduced apoptosis in the infarct area and improved cardiac functions.
|
15800659 |
2005 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the relation between the expressions of HO-1 and the effects of human bone marrow mesenchymal cells (MSCs) transplantation to xenogenic rat hearts with experimental myocardial infarction (MI).
|
15797262 |
2005 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
BEFREE |
The study population consisted of 1972 control subjects and 597 subjects with ischemic heart disease (myocardial infarction (MI) n = 393, HMOX1 n = 204).
|
15064108 |
2004 |
|
Myocardial Infarction
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
AAV-mediated transfer of the hHO-1 gene 8 weeks before acute coronary artery ligation and release led to a dramatic reduction (>75%) in left ventricular myocardial infarction.
|
11827926 |
2002 |
|
Myocardial Infarction
|
0.300 |
Biomarker
|
disease |
RGD |
We, therefore, examined the expression and localization of HO-1 in a rat experimental myocardial infarction model.
|
12392996 |
2002 |