FOXA1, forkhead box A1, 3169

N. diseases: 138; N. variants: 1
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 Biomarker group BEFREE Analysis of xenograft mouse models confirmed FOXA1 loss in NEPC tumors relative to its adenocarcinoma counterparts. 28319070 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 AlteredExpression group BEFREE Most (90%) pre-invasive lesions (CIN3 and in situ adenocarcinomas) strongly expressed FOXA1 and this difference from invasive lesions was statistically significant (p=0.005). 28209524 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 Biomarker group BEFREE Positive staining for FOXA1 was seen in 34.7% of the SCC samples, which was comparable with 39.6% in the AC samples. 22383183 2012
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 AlteredExpression group LHGDN The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. 12234996 2002
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.050 AlteredExpression group BEFREE Molecular cloning of the forkhead transcription factor HNF-3 alpha from a human pulmonary adenocarcinoma cell line. 8652662 1996