HOXA1, homeobox A1, 3198

N. diseases: 95; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.040 GeneticVariation disease BEFREE In line with this notion, a nonsynonymous single nucleotide polymorphism within a highly conserved domain of HOXA1--rs10951154" genes_norm="3198">A218G (rs10951154)--has been linked to both ASD risk, and cross-sectional differences in superior posterior lobar cerebellar anatomy in late adulthood. 22359339 2012
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.040 GeneticVariation disease BEFREE The rs10951154" genes_norm="3198">A218G (rs10951154) in HOXA1 and the insertion variant in HOXB1 (nINS/INS, rs72338773) were of special interest for ASD but with inconclusive results. 21980499 2011
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.040 GeneticVariation disease BEFREE A possible role for Hoxa1 genotype in susceptibility to autism spectrum disorders was recently proposed. 12027529 2002
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.040 Biomarker disease BEFREE The results support a role for HOXA1 in susceptibility to autism, and add to the existing body of evidence implicating early brain stem injury in the etiology of ASDs. 11091361 2000