HOXA13, homeobox A13, 3209

N. diseases: 126; N. variants: 7
Disease: Hypospadias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.320 Biomarker disease RGD Maternal exposure to di-n-butyl phthalate (DBP) induces combined anorectal and urogenital malformations in male rat offspring. 27079746 2016
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.320 Biomarker disease BEFREE Hypospadias in the Hoxa13 -/- mice occurs as a result of the combined loss of Fgf8 and Bmp7 expression in the UPE. 17264867 2007
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.320 Biomarker disease BEFREE Mice mutant for Hoxa13 also exhibit changes in androgen receptor expression, providing a developmental link between Hoxa13-associated hypospadias and those produced by antagonists to androgen signaling. 12783783 2003
CUI: C0848558
Disease: Hypospadias
Hypospadias 		0.320 Biomarker disease HPO