HOXB9, homeobox B9, 3219

N. diseases: 83; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 Biomarker disease CTD_human We also demonstrate that the endocrine disrupting chemical bisphenol-A (BPA) induces HOXB9 expression in cultured human breast cancer cells (MCF7) as well as in vivo in the mammary glands of ovariectomized (OVX) rats. 27182052 2016
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE We also demonstrate that the endocrine disrupting chemical bisphenol-A (BPA) induces HOXB9 expression in cultured human breast cancer cells (MCF7) as well as in vivo in the mammary glands of ovariectomized (OVX) rats. 27182052 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 AlteredExpression disease BEFREE We also demonstrate that the endocrine disrupting chemical bisphenol-A (BPA) induces HOXB9 expression in cultured human breast cancer cells (MCF7) as well as in vivo in the mammary glands of ovariectomized (OVX) rats. 27182052 2016
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 Biomarker disease CTD_human We also demonstrate that the endocrine disrupting chemical bisphenol-A (BPA) induces HOXB9 expression in cultured human breast cancer cells (MCF7) as well as in vivo in the mammary glands of ovariectomized (OVX) rats. 27182052 2016
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE The induction of HOXB9 expression by E2F1 was observed by Q-PCR in several breast cancer cell lines overexpressing E2F1. 25136922 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 AlteredExpression disease BEFREE The induction of HOXB9 expression by E2F1 was observed by Q-PCR in several breast cancer cell lines overexpressing E2F1. 25136922 2014
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE Our studies demonstrated that HOXB9 is overexpressed in breast cancer tissue. 22863320 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 Biomarker disease BEFREE We show that HXR9 causes apoptosis in a number of breast cancer-derived cell lines and that sensitivity to HXR9 is directly related to the averaged expression of HOX genes HOXB1 through to HOXB9, providing a potential biomarker to predict the sensitivity of breast tumors to HXR9 or its derivatives. 23053648 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 Biomarker disease BEFREE We show that HXR9 causes apoptosis in a number of breast cancer-derived cell lines and that sensitivity to HXR9 is directly related to the averaged expression of HOX genes HOXB1 through to HOXB9, providing a potential biomarker to predict the sensitivity of breast tumors to HXR9 or its derivatives. 23053648 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 AlteredExpression disease BEFREE Our studies demonstrated that HOXB9 is overexpressed in breast cancer tissue. 22863320 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.350 AlteredExpression disease BEFREE Thus, deregulated expression of HOXB9 contributes to breast cancer progression and lung metastasis by inducing several growth factors that alter tumor-specific cell fates and the tumor stromal microenvironment. 20080567 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.350 AlteredExpression disease BEFREE Thus, deregulated expression of HOXB9 contributes to breast cancer progression and lung metastasis by inducing several growth factors that alter tumor-specific cell fates and the tumor stromal microenvironment. 20080567 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.310 Biomarker group CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.310 Biomarker group BEFREE We show that HXR9 causes apoptosis in a number of breast cancer-derived cell lines and that sensitivity to HXR9 is directly related to the averaged expression of HOX genes HOXB1 through to HOXB9, providing a potential biomarker to predict the sensitivity of breast tumors to HXR9 or its derivatives. 23053648 2012
CUI: C2930974
Disease: Acute erythroleukemia
Acute erythroleukemia 		0.300 Biomarker disease CTD_human Genomic subtyping and therapeutic targeting of acute erythroleukemia. 30926971 2019
CUI: C2930975
Disease: Acute erythroleukemia - M6a subtype
Acute erythroleukemia - M6a subtype 		0.300 Biomarker disease CTD_human Genomic subtyping and therapeutic targeting of acute erythroleukemia. 30926971 2019
CUI: C2930976
Disease: Acute myeloid leukemia FAB-M6
Acute myeloid leukemia FAB-M6 		0.300 Biomarker disease CTD_human Genomic subtyping and therapeutic targeting of acute erythroleukemia. 30926971 2019
CUI: C2930977
Disease: Acute erythroleukemia - M6b subtype
Acute erythroleukemia - M6b subtype 		0.300 Biomarker disease CTD_human Genomic subtyping and therapeutic targeting of acute erythroleukemia. 30926971 2019
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.300 Biomarker group CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C0042138
Disease: Uterine Neoplasms
Uterine Neoplasms 		0.300 Biomarker group CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C0153567
Disease: Uterine Cancer
Uterine Cancer 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016