HOXC10, homeobox C10, 3226

N. diseases: 43; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.020 Biomarker disease BEFREE <b>Conclusions:</b> This study suggests that HOXC10 induces glioma angiogenesis by transcriptionally upregulating <i>VEGFA</i> expression, and may represent a potential target for antiangiogenic therapy in gliomas. 30429891 2018
CUI: C0017638
Disease: Glioma
Glioma
0.020 Biomarker disease BEFREE In summary, our results suggest that HOXC10 upregulation in glioma promotes an aggressive phenotype and induces immunosuppressive gene expression, supporting further investigation of the potential of HOXC10 as a therapeutic target in glioma. 29676849 2018