Childhood Acute Lymphoblastic Leukemia
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
The p.Glu81Val mutation of HOXD4 thus results in a partial loss-of-function, which might be involved in childhood ALL.
|
15776434 |
2005 |
Childhood Acute Lymphoblastic Leukemia
|
0.310 |
Biomarker
|
disease |
CTD_human |
The p.Glu81Val mutation of HOXD4 thus results in a partial loss-of-function, which might be involved in childhood ALL.
|
15776434 |
2005 |
L2 Acute Lymphoblastic Leukemia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Mutation analysis of the HOX paralogous 4-13 genes in children with acute lymphoid malignancies: identification of a novel germline mutation of HOXD4 leading to a partial loss-of-function.
|
15776434 |
2005 |
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Mutation analysis of the HOX paralogous 4-13 genes in children with acute lymphoid malignancies: identification of a novel germline mutation of HOXD4 leading to a partial loss-of-function.
|
15776434 |
2005 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Cellular results revealed that HOXD4 can promote tumor cell proliferation by upregulating c-Myc and cyclin D1.
|
30588951 |
2019 |
Gastric Adenocarcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The role of HOXD4 in human gastric adenocarcinoma has not been elucidated.
|
30588951 |
2019 |
Secondary malignant neoplasm of lymph node
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
High expression of HOXD4 was significantly associated with larger tumor size (P = 0.008), advanced tumor invasion depth (P = 0.014), and positive lymph node metastasis (P < 0.001).
|
30588951 |
2019 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
The effects and mechanisms of HOXD4 on cell proliferation, migration and invasion were explored through cellular experiments.
|
30588951 |
2019 |
Glioma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Clinicopathological analysis of HOXD4 expression in 453 glioma patients was performed in the current study.
|
29383189 |
2017 |
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
As a component of HOX clusters, HOXD4 plays a controversial role in the tumorigenesis of central nervous system.
|
29383189 |
2017 |
Arachnoid Cysts
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Identification of HOXD4 Mutations in Spinal Extradural Arachnoid Cyst.
|
26545093 |
2015 |
Malignant Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Mutation analysis of the HOX paralogous 4-13 genes in children with acute lymphoid malignancies: identification of a novel germline mutation of HOXD4 leading to a partial loss-of-function.
|
15776434 |
2005 |
Acute lymphocytic leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The p.Glu81Val mutation of HOXD4 thus results in a partial loss-of-function, which might be involved in childhood ALL.
|
15776434 |
2005 |
Adult Acute Lymphocytic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The p.Glu81Val mutation of HOXD4 thus results in a partial loss-of-function, which might be involved in childhood ALL.
|
15776434 |
2005 |
Refractory anemias
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Low levels of HOXD4 and HOXD9 induction were observed in two and one RA-treated NB cell line, respectively.
|
7501971 |
1996 |
Rheumatoid Arthritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Low levels of HOXD4 and HOXD9 induction were observed in two and one RA-treated NB cell line, respectively.
|
7501971 |
1996 |