HOXD8, homeobox D8, 3234

N. diseases: 21; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 AlteredExpression disease BEFREE HOXD8 directly activates the transcription of HOXC9, a key effector of RA action in neuroblastoma cells. 22879880 2012
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 AlteredExpression disease BEFREE However, a significant induction of HOXC6, HOXD1, and HOXD8 expression is seen in the RA-treated NB cell lines, albeit with different patterns and degree of up-regulation. db-cAMP treatment also induced HOXC6 and HOXD8 expression in two of the three NB cell lines analyzed. 7501971 1996