HOXD10, homeobox D10, 3236

N. diseases: 83; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 CausalMutation disease CLINVAR
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 Biomarker disease HPO
CUI: C0003864
Disease: Arthritis
Arthritis 		0.100 Biomarker disease HPO
CUI: C1860449
Disease: Equinus calcaneus
Equinus calcaneus 		0.100 Biomarker phenotype HPO
CUI: C1860450
Disease: Calcaneovalgus deformity
Calcaneovalgus deformity 		0.100 Biomarker disease HPO
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.010 AlteredExpression disease BEFREE One epithelial Wilm's tumor expressed only an aberrant 0.3 kb HOXD10 transcript. 7967520 1994
CUI: C0431943
Disease: Lower Extremity Deformities, Congenital
Lower Extremity Deformities, Congenital 		0.300 Biomarker group CTD_human Targeted disruption of Hoxd-10 affects mouse hindlimb development. 9409668 1997
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 AlteredExpression group BEFREE HoxD10 expression was higher in quiescent as compared to tumor-associated angiogenic endothelium. 12466126 2002
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 Biomarker disease GENOMICS_ENGLAND A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 GeneticVariation disease UNIPROT A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 GeneticVariation disease BEFREE This paper presents four generations of a family with radiographically demonstrated congenital vertical talus (CVT) in whom a HOXD10 gene mutation was identified. 15368082 2004
CUI: C0240912
Disease: Vertical Talus
Vertical Talus 		0.740 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0007959
Disease: Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disease 		0.320 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0007959
Disease: Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disease 		0.320 GeneticVariation disease LHGDN A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0016202
Disease: Flatfoot
Flatfoot 		0.300 Biomarker phenotype CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0152237
Disease: Talipes Calcaneovalgus
Talipes Calcaneovalgus 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0205713
Disease: Roussy-Levy Syndrome (disorder)
Roussy-Levy Syndrome (disorder) 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0270911
Disease: Charcot-Marie-Tooth Disease, Type Ia (disorder)
Charcot-Marie-Tooth Disease, Type Ia (disorder) 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0270912
Disease: Charcot-Marie-Tooth Disease, Type Ib
Charcot-Marie-Tooth Disease, Type Ib 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0270914
Disease: Hereditary Motor and Sensory-Neuropathy Type II
Hereditary Motor and Sensory-Neuropathy Type II 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0751036
Disease: Hereditary Motor and Sensory Neuropathy Type I
Hereditary Motor and Sensory Neuropathy Type I 		0.300 Biomarker disease CTD_human A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C1860446
Disease: Congenital vertical talus, bilateral
Congenital vertical talus, bilateral 		0.300 GermlineCausalMutation phenotype ORPHANET A HOX gene mutation in a family with isolated congenital vertical talus and Charcot-Marie-Tooth disease. 15146389 2004
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE Taken together, our results suggest that HoxD10 has tumor-suppressive functions for mammary epithelial cells. 16103068 2005
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.020 AlteredExpression group BEFREE We observed that HoxD10 expression is progressively reduced in epithelial cells as malignancy increases in both breast and endometrial tumors. 16103068 2005
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.020 AlteredExpression group BEFREE We observed that HoxD10 expression is progressively reduced in epithelial cells as malignancy increases in both breast and endometrial tumors. 16103068 2005