APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 Biomarker group CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 GeneticVariation group BEFREE The genomic profiling demonstrated mutations in APC(73%), KRAS (33%), ARID1A and PIK3CA (6.7%) genes between primary colorectal and metastatic liver tumors. 24599305 2014
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 GeneticVariation group BEFREE Multifocal hepatic neoplasia in 3 children with APC gene mutation. 23715166 2013
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 Biomarker group BEFREE Furthermore, our data strengthen a role for impaired APC function in the pathogenesis of adrenal and hepatic neoplasms in FAP patients. 15287021 2004
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 GeneticVariation group BEFREE Additional reports will confirm whether inherited APC gene mutations between codon 1444 and 1578 increase the risk for hepatic tumors. 9041254 1997
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.540 Biomarker group MGD