AIRE, autoimmune regulator, 326

N. diseases: 175; N. variants: 85
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease MGD Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity. 17360567 2007
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease MGD Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. 15699112 2005
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease MGD Modifier loci condition autoimmunity provoked by Aire deficiency. 16172259 2005
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease MGD Projection of an immunological self shadow within the thymus by the aire protein. 12376594 2002
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease MGD Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. 11854172 2002
CUI: C1855868
Disease: Polyglandular Deficiency Syndrome, Persian-Jewish Type
Polyglandular Deficiency Syndrome, Persian-Jewish Type 		0.500 Biomarker disease CTD_human