AIRE, autoimmune regulator, 326

N. diseases: 175; N. variants: 85
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease MGD Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity. 17360567 2007
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease MGD Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. 15699112 2005
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease MGD Modifier loci condition autoimmunity provoked by Aire deficiency. 16172259 2005
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease MGD Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. 11854172 2002
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease MGD Projection of an immunological self shadow within the thymus by the aire protein. 12376594 2002
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 Biomarker disease CTD_human
CUI: C1855869
Disease: Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant 		0.600 CausalMutation disease CLINVAR