BIRC2, baculoviral IAP repeat containing 2, 329

N. diseases: 125; N. variants: 3
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.310 AlteredExpression disease BEFREE Our data demonstrate that ARC is regulated via BIRC2/MAP3K14 signalling and its overexpression in AML or MSCs can function as a resistant factor to birinapant-induced leukaemia cell death, suggesting that strategies to inhibit ARC will improve the therapeutic potential of SMAC mimetics. 25079338 2014
CUI: C0023418
Disease: leukemia
leukemia 		0.310 Biomarker disease CTD_human A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells. 12970779 2003