BIRC2, baculoviral IAP repeat containing 2, 329

N. diseases: 125; N. variants: 3
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.330 Biomarker disease BEFREE IRF-1 inhibits NF-κB activity, suppresses TRAF2 and cIAP1 and induces breast cancer cell specific growth inhibition. 26011589 2015
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.330 AlteredExpression disease BEFREE Moreover, exposure of NB and breast cancer cells to CFM-4 or -5 resulted in diminished expression of anti-apoptotic XIAP1, cIAP1, and Survivin proteins. 25033461 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.330 Biomarker disease BEFREE Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. 24422988 2014
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.330 Biomarker disease CTD_human Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K. 25330770 2014