BIRC2, baculoviral IAP repeat containing 2, 329

N. diseases: 125; N. variants: 3
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE To address these issues, we herein developed a liposomal formulation of API-1 to improve API-1 delivery and enhance its anti-HCC efficacy. 31367251 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development. 29381806 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE Nimbolide induced apoptosis by activating ERK-mediated inhibition of c-IAP1 expression in human hepatocellular carcinoma cells. 29962003 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE The mRNA and protein expressions of IAPs, including cellular IAPs (cIAP1 and cIAP2) and X chromosome-linked IAP (XIAP), were increased in HCC tumors compared with normal liver tissue. 30459627 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE We have found that LCL161 targets (cIAP1, cIAP2 and XIAP) were up-regulated in HCC tumours. 24976294 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Integration of high-resolution copy number profiles of mouse tumor models and human tumors identified cIAP1 and Yap as oncogenes in human hepatocellular carcinoma, while NEDD9 was identified as a metastasis gene in human melanoma. 16843259 2006