Schizophrenia
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Association Studies of HSPA1A and HSPA1L Gene Polymorphisms With Schizophrenia.
|
30342847 |
2018 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
PSYGENET |
In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population.
|
23893339 |
2014 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
PSYGENET |
We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ).
|
19439993 |
2009 |
Schizophrenia
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ).
|
19439993 |
2009 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
BEFREE |
Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported.
|
18299791 |
2008 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
PSYGENET |
Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported.
|
18299791 |
2008 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
BEFREE |
This study aimed to investigate the association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia.
|
15963589 |
2005 |
Schizophrenia
|
0.340 |
Biomarker
|
disease |
PSYGENET |
There were no significant differences in the allelic or genotype frequencies of the HSPA1A and HSPA1L polymorphisms between the schizophrenia patients and the controls, while there was a marginal difference in the genotype frequency of the HSPA1B polymorphisms, and a significant difference in the allelic frequency of the HSPA1B polymorphisms between the schizophrenia patients and the controls.
|
15963589 |
2005 |
Paranoid Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to determine whether genetic variants in the HSPA1A (rs1008438, rs562047) and HSPA1L (rs2075800) genes are associated with the risk of paranoid schizophrenia and the clinical presentation of the disease.
|
30342847 |
2018 |
Paranoid Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population.
|
23893339 |
2014 |
Major depression, single episode
|
0.300 |
Biomarker
|
disease |
PSYGENET |
One hundred and forty two hospitalised patients, affected by major depression and treated with antidepressants drugs for a major depressive episode were evaluated for depressive severity at the baseline and at the discharge and genotyped for five SNPs within the genes HSPA1L, HSPA1A and HSPA1B.
|
17428599 |
2007 |
Unipolar Depression
|
0.300 |
Biomarker
|
disease |
PSYGENET |
One hundred and forty two hospitalised patients, affected by major depression and treated with antidepressants drugs for a major depressive episode were evaluated for depressive severity at the baseline and at the discharge and genotyped for five SNPs within the genes HSPA1L, HSPA1A and HSPA1B.
|
17428599 |
2007 |
Major Depressive Disorder
|
0.300 |
Biomarker
|
disease |
PSYGENET |
One hundred and forty two hospitalised patients, affected by major depression and treated with antidepressants drugs for a major depressive episode were evaluated for depressive severity at the baseline and at the discharge and genotyped for five SNPs within the genes HSPA1L, HSPA1A and HSPA1B.
|
17428599 |
2007 |
Drug Allergy
|
0.300 |
Biomarker
|
group |
CTD_human |
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.
|
16538175 |
2006 |
Multiple Sclerosis
|
0.120 |
GeneticVariation
|
disease |
BEFREE |
We reported a strong association between rs2227956 polymorphism and MS risk, which is independent from the association with HSP70-2 rs1061581, and a significant link between hsp70-hom protein expression and MS severity.
|
27609295 |
2016 |
Multiple Sclerosis
|
0.120 |
GeneticVariation
|
disease |
GWASDB |
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
|
20598377 |
2010 |
Multiple Sclerosis
|
0.120 |
Biomarker
|
disease |
BEFREE |
Despite the strength of the association of multiple sclerosis (MS) and human leukocyte antigen (HLA)-DR2, other genetic elements could have a role in the pathophysiology of MS. We investigated possible associations with polymorphic susceptibility genes located within the HLA complex, i.e., heat-shock protein (HSP)70-1, HSP70-2, and HSP70-hom in Japanese patients with MS.
|
11696222 |
2001 |
Chronic Obstructive Airway Disease
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
There was no evidence for the association of hsp70-hom (+2437T/C), TNF-α (+489G/A) SNPs and HMOX-1 (number of GT repeats) polymorphism with COPD.
|
22542718 |
2012 |
Rheumatoid Arthritis
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
Rheumatoid Arthritis
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
Rheumatoid Arthritis
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
Diabetes Mellitus, Insulin-Dependent
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
Rheumatoid Arthritis
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Analysis of 60 rheumatoid arthritis (RA) families, each with an affected sib-pair, revealed an association between hsp70-hom A-2763 and RA using both the transmission disequilibrium test (TDT) and the transmission to sib-pair (Tsp) test (P=0.0038 and P=0.013, respectively).
|
10958354 |
2000 |
Diabetes Mellitus, Insulin-Dependent
|
0.110 |
Biomarker
|
disease |
BEFREE |
Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM).
|
7901896 |
1993 |
Chronic Obstructive Airway Disease
|
0.110 |
GeneticVariation
|
disease |
CLINVAR |
|
|
|