Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE In addition, HSP70 was upregulated in human neuroblastoma cells (SK-N-SH) infected with EV71. 30579945 2019
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker disease BEFREE Using LC-MS/MS and Western blotting, we identified the members of the Heat Shock 70-kDa family of proteins (HSP70) as potential TDF-R candidates in both MCF7 and BT-549 human breast cancer cells (HBCC) and PC3, DU145, and LNCaP human prostate cancer cells (HPCC), but not in HeLa cells, NG108 neuroblastoma, or HDF-a and BLK CL.4 cells fibroblasts or fibroblast-like cells. 31347062 2019
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE Effects of celastrol on Tau hyperphosphorylation and expression of HSF-1 and HSP70 in SH-SY5Y neuroblastoma cells induced by amyloid-β peptides. 29274099 2018
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE Neither exposure to ELF-MF or AlCl<sub>3</sub> alone induced DNA damage, changes in GSH/GSSG ratio or variations in Hsp70 expression with respect to the controls in both NB cell lines. 28985943 2017
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE The present study investigated the promotion of Hsp70 expression in SH‑SY5Y neuroblastoma cells by glutamine (Gln), which has recently been recognized to induce Hsp70 expression. 26135068 2015
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker disease BEFREE Endogenous merlin and hsp70 proteins interacted in HEI-193 schwannoma and SK-N-AS neuroblastoma cells. 21903608 2011
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker disease BEFREE Neuroblastoma cells were transfected with Hsp-70-specific siRNA. 20638672 2010
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE Our objectives were to assess the effectiveness of triptolide, an Hsp-70 inhibitor, in treating neuroblastoma in vitro and in vivo, and to measure the associated effects on Hsp-70 levels and apoptosis markers. 19628086 2009
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker disease BEFREE In vitro, Tat-Hsp70 transduced neuroblastoma cells and protected primary mesencephalic DA neurons and their neurites against MPP+-mediated degeneration. 18182047 2008
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker disease BEFREE Our findings shed light on the post-transcriptional regulation of HSP70 expression, suggesting the existence of a new molecular cascade -involving PKC/HuR/HSP70- that possibly represents an early event in the cellular response to H(2)O(2)-mediated oxidative stress in SH-SY5Y human neuroblastoma cells. 18991684 2008
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE Furthermore, the addition of toxic TTR aggregates to cultures of human and rodent neuroblastoma cell lines induced upregulation of Hsp70 and Hsp27. 18431252 2008
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE HSP27 was less expressed, whereas HSP70 was more expressed in the immature areas of NB. 18066588 2008
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE The results indicate that 8-Br-cAMP could facilitate synthesis of NO in the neuroblastoma HXO-Rb44 cells, which could have tendency toward neuron development, suggesting that the increased hsp70, NO and NOS may involve cell differentiation of the retinoblastoma HXO-Rb44. 11775244 2000
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression disease BEFREE The possible mechanism of this reduced Hsp70 expression was studied in thermally stressed murine neuroblastoma cells (N18). 10588512 1999