Disease: Major Depressive Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.340 Biomarker disease BEFREE In women who developed MDD, HSP70 and 3-nitrotyrosine were elevated at baseline, whereas TBARS were elevated 6 months prior to development of MDD, as compared to those who did not develop MDD. 28550365 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.340 AlteredExpression disease BEFREE An increased expression of the TLR-4 endogenous ligand Hsp70 (+ 33%), but not of Hsp60, and the activated forms of mitogen-activated protein kinases (MAPKs) p38 (+ 47%) and JNK (+ 56%) was observed in MDD. 30180869 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.340 AlteredExpression disease BEFREE Further studies are required to determine the amounts of HSP70 and its mRNA in stress disorders such as major depression. 12763290 2003
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.340 GeneticVariation disease BEFREE The allel-specific abnormal transcript of the HSP70 gene on chromosome 6 thus may underlie the altered stress and/or immune response in major depression. 8645252 1996