Filariasis
|
0.010 |
Biomarker
|
disease |
BEFREE |
ELISA with a purified beta-galactosidase fusion protein from B. pahangi showed antibody responses to hsc70 across the clinical spectrum of filariasis.
|
2659668 |
1989 |
Infection by Wuchereria bancrofti
|
0.010 |
Biomarker
|
disease |
BEFREE |
However, ELISA with recombinant fusion proteins for both Plasmodium falciparum and Schistosoma mansoni hsc70 indicated that some individuals with Brugian or Bancroftian filariasis did produce antibodies which cross-reacted with plasmodial and schistosomal homologs.
|
2659668 |
1989 |
Reticulosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937.
|
8033225 |
1993 |
Diffuse Large B-Cell Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937.
|
8033225 |
1993 |
Histiocytic sarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Regulation of hsc70 expression in the human histiocytic lymphoma cell line, U937.
|
8033225 |
1993 |
Herpes Simplex Infections
|
0.030 |
AlteredExpression
|
group |
BEFREE |
cis-acting elements involved in transcriptional regulation of the herpes simplex virus type 1 latency-associated promoter 1 (LAP1) in vitro and in vivo.
|
8764049 |
1996 |
Lung Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Identification and characterization of a novel hsc70-like gene in the human lung tumor cell line HS24.
|
9115634 |
1997 |
melanoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
These data indicate that HSC71 molecules are expressed on human melanoma cell line P36, and that HSC71 may play a potential role in Ag presentation and processing of T. gondii-infected P36 cells to CD4+ CTL.
|
9272701 |
1997 |
Transient Ischemic Attack
|
0.200 |
Biomarker
|
disease |
RGD |
Assembly of proteins to postsynaptic densities after transient cerebral ischemia.
|
9425004 |
1998 |
Graft-vs-Host Disease
|
0.200 |
Biomarker
|
disease |
RGD |
Expression of 70-kDa heat-shock protein during acute graft-versus-host disease.
|
9557158 |
1998 |
Reperfusion Injury
|
0.300 |
Therapeutic
|
disease |
CTD_human |
Heat-shock protein-73 protects against small intestinal warm ischemia-reperfusion injury in the rat.
|
10216529 |
1999 |
Metabolic Diseases
|
0.210 |
Biomarker
|
group |
RGD |
Our findings demonstrated that HSP73 and HSP90 chaperone proteins specifically accumulated within lysosomes of proximal tubular epithelial cells during the course of PDGA-induced acute lysosomal thesaurismosis.
|
10469394 |
1999 |
Breast Carcinoma
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
In both cases, mutation was coincident with allelic imbalance, suggesting that HSC70 is a target of somatic mutation and deletion in a fraction of breast carcinomas.
|
10485459 |
1999 |
Paraneoplastic Syndromes, Ocular
|
0.200 |
Biomarker
|
disease |
RGD |
Cancer-associated retinopathy induced by both anti-recoverin and anti-hsc70 antibodies in vivo.
|
10586938 |
1999 |
Malignant tumor of colon
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, this is the first study demonstrating the expression of NIP(71) in human colon cancer cell lines and a possible relationship to colon carcinogenesis.
|
10891381 |
2000 |
Colon Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, this is the first study demonstrating the expression of NIP(71) in human colon cancer cell lines and a possible relationship to colon carcinogenesis.
|
10891381 |
2000 |
Carcinogenesis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Furthermore, this is the first study demonstrating the expression of NIP(71) in human colon cancer cell lines and a possible relationship to colon carcinogenesis.
|
10891381 |
2000 |
Rheumatoid Arthritis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Quantitative precipitation assay from total cellular proteins and from lysosomal extracts demonstrated that RA-associated HLA-DRB1 alleles bound Hsp73 better than did HLA-DRB1 alleles that were not associated with RA.
|
11953969 |
2002 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
HSC70 was also detected in the majority (97%) of cases, although expression was not correlated with BAG-1 levels, oestrogen receptor status or tumour grade.
|
12081204 |
2002 |
Invasive carcinoma of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Immunohistochemistry was used to examine the expression of BAG-1 and HSC70 in 160 cases of invasive breast cancer.
|
12081204 |
2002 |
Chemical and Drug Induced Liver Injury
|
0.200 |
Biomarker
|
disease |
RGD |
Immunohistochemical studies on the expression pattern of molecular chaperones HSC70 and HSP25 and cell cycle-related proteins cyclin D1 and PCNA in rat liver after thioacetamide intoxication.
|
12376827 |
2002 |
Kidney Failure, Acute
|
0.010 |
Biomarker
|
disease |
BEFREE |
We have investigated the association of genetic polymorphisms of the constitutive HSP70 (HSP73) and the inducible HSP70 (HSP72) encoding genes with the risk of acute renal failure (ARF) in very low birth weight (VLBW) neonates.
|
12840151 |
2003 |
Very Low Birth Weight
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We have investigated the association of genetic polymorphisms of the constitutive HSP70 (HSP73) and the inducible HSP70 (HSP72) encoding genes with the risk of acute renal failure (ARF) in very low birth weight (VLBW) neonates.
|
12840151 |
2003 |
Malignant tumor of colon
|
0.020 |
Biomarker
|
disease |
BEFREE |
We demonstrated in this study that the HSC70 gene encodes two antigenic peptides recognised by HLA-B46-restricted and tumour-reactive CTLs established from tumour-infiltrating lymphocytes of a colon cancer.
|
12966429 |
2003 |
Colon Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
We demonstrated in this study that the HSC70 gene encodes two antigenic peptides recognised by HLA-B46-restricted and tumour-reactive CTLs established from tumour-infiltrating lymphocytes of a colon cancer.
|
12966429 |
2003 |