Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.330 AlteredExpression disease BEFREE HSP27 expression was increased in patients with MM compared with healthy control subjects, and the expression was increased as the cancer progressed (P<0.05). 31322176 2019
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.330 AlteredExpression disease BEFREE In conclusion, these results indicate that 17-AAG-mediated induction of HSP70 and HSP27 expression can be attenuated by Act D and therefore can potentially improve the clinical treatment of multiple myeloma. 19383903 2009
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.330 Biomarker disease CTD_human These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells. 12855565 2003
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.330 AlteredExpression disease LHGDN These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells. 12855565 2003