|
Colorectal Carcinoma
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
Further studies are warranted on the apoptotic mechanisms linked to the reciprocal regulation of BMF and BIRC5 in human colorectal cancers characterized by Eomes overexpression.
|
27539959 |
2016 |
|
Colorectal Carcinoma
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
DR5, BIRC5/Survivin, XIAP, c-IAP1 and c-IAP2 mRNA expression are significantly deregulated in CRC and could provide a panel of markers with significant discriminatory value between CRC and normal colorectal tissue.
|
27827395 |
2016 |
|
Colorectal Carcinoma
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor.
|
26277021 |
2015 |
|
Colorectal Carcinoma
|
0.390 |
Biomarker
|
disease |
BEFREE |
In conclusion, we demonstrated that high miR-218 expression had a positive prognostic value in 5-FU-based treatments for CRC patients and discovered a novel mechanism mediated by miR-218 to promote apoptosis and to function synergistically with 5-FU to promote chemosensitivity by suppressing BIRC5 and TS in CRC.
|
26442524 |
2015 |
|
Colorectal Carcinoma
|
0.390 |
Biomarker
|
disease |
BEFREE |
Serum cell free BIRC5 mRNA is a promising non-invasive biomarker for diagnosis and prognosis of CRC.
|
24338523 |
2014 |
|
Colorectal Carcinoma
|
0.390 |
Biomarker
|
disease |
BEFREE |
Survivin/BIRC5 is a potentially interesting prognostic marker and therapeutic target in colorectal cancer (CRC).
|
23755220 |
2013 |
|
Colorectal Carcinoma
|
0.390 |
AlteredExpression
|
disease |
BEFREE |
The results showed VEGF (71.4%), SOX9 (68.8%), MYC (62.3%), CCND1 (59.7%), TP53 (59.4%), MMP9 (53.3%), and BIRC5 (50.6%) as significantly overexpressed genes in CRC tissues.
|
24240588 |
2013 |
|
Colorectal Carcinoma
|
0.390 |
Biomarker
|
disease |
BEFREE |
This review summarizes the current knowledge about the splice isoforms of VEGFA, UGT1A, PXR, cyclin D1, BIRC5 (survivin), DPD, K-RAS, SOX9, SLC39A14 and other genes, which may be possible therapeutic targets for colorectal cancer.
|
23118106 |
2012 |
|
Colorectal Carcinoma
|
0.390 |
Biomarker
|
disease |
CTD_human |
Overexpression of thymosin beta-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively.
|
16364925 |
2006 |
|
Colorectal Carcinoma
|
0.390 |
GeneticVariation
|
disease |
BEFREE |
Infection with pAd-T34A caused spontaneous apoptosis in cell lines of breast, cervical, prostate, lung, and colorectal cancer.
|
11581299 |
2001 |