HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Mood Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker group BEFREE Dysfunction of the serotonin (5-HT1A) receptor (5-HTR1A) has been implicated in mood disorders, anxiety disorders, psychosis and the action of antidepressants. 15469667 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 GeneticVariation group BEFREE Genetic variation at the 5HT1A and 5HT2C receptor genes does not, therefore, play a major role in the pathogenesis of mood disorders symptomatology.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:161-166, 2000. 10893489 2000
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker group BEFREE Converging evidence from postmortem studies of mood disorders suggests these reductions of 5HT1A receptor BP may be associated with histopathological changes involving the raphe. 10578452 1999
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker group BEFREE These results suggest that the 5-HT1A receptor gene is intact in mood disorders. 7612160 1995