HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Absence Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Biomarker phenotype BEFREE The present results suggest that the serotonergic system negatively regulates the incidence of absence seizures by stimulation of 5-HT(1A) and 5-HT(2) receptors. 20736508 2010
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Therapeutic phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Biomarker phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Therapeutic phenotype CTD_human Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. 12646302 2003
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Biomarker phenotype CTD_human Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. 12646302 2003
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Biomarker phenotype CTD_human The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms. 2533336 1989
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.310 Therapeutic phenotype CTD_human The role of the central serotonergic system in pilocarpine-induced seizures: receptor mechanisms. 2533336 1989