HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 Biomarker disease HPO
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.700 Biomarker disease CTD_human
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker disease HPO
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker disease CTD_human
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		0.510 Biomarker disease CTD_human
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.500 Biomarker disease HPO
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.400 Biomarker disease CTD_human
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.300 Biomarker disease CTD_human
CUI: C0011574
Disease: Involutional Depression
Involutional Depression 		0.300 Biomarker disease CTD_human
CUI: C1571983
Disease: Involutional paraphrenia
Involutional paraphrenia 		0.300 Biomarker disease CTD_human
CUI: C1571984
Disease: Psychosis, Involutional
Psychosis, Involutional 		0.300 Biomarker disease CTD_human
CUI: C0018524
Disease: Hallucinations
Hallucinations 		0.170 Biomarker disease HPO
CUI: C0003467
Disease: Anxiety
Anxiety 		0.150 Biomarker disease HPO
CUI: C0011253
Disease: Delusions
Delusions 		0.140 Biomarker disease HPO
CUI: C0027562
Disease: Negativism
Negativism 		0.100 Biomarker phenotype HPO
CUI: C0424290
Disease: Compulsive hoarding
Compulsive hoarding 		0.100 Biomarker disease HPO
CUI: C0497552
Disease: Congenital neurologic anomalies
Congenital neurologic anomalies 		0.100 Biomarker group HPO
CUI: C1696701
Disease: Skin-picking
Skin-picking 		0.100 Biomarker disease HPO
CUI: C1866986
Disease: Social and occupational deterioration
Social and occupational deterioration 		0.100 Biomarker phenotype HPO
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker disease BEFREE Given this result, we conclude that the serotonin 5-HT2 receptor gene itself is not a major susceptibility gene for schizophrenia in this family. 1348924 1992
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 GeneticVariation disease BEFREE We looked for an association between schizophrenia and this variant of the 5-HT2a-receptor gene in a large multicentre study. 8622505 1996
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 GeneticVariation disease BEFREE This finding suggests that genetic predisposition to schizophrenia may be affected by a functional 5-HT2A receptor variant that is in linkage disequilibrium with 102T/C. 8655141 1996
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 GeneticVariation disease BEFREE Our results suggest that an abnormality in the 5-HT2A receptor gene in schizophrenia is unlikely. 8703302 1996
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 GeneticVariation disease BEFREE The positive association we report here would suggest that the DNA region with susceptibility to schizophrenia lies in the HTR2A on the long arm of chromosomes 13. 8678105 1996
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 GeneticVariation disease BEFREE This study does not support an association between the 5-HT2 receptor gene locus and schizophrenia or subgroups based on treatment response. 8925254 1996