HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 211; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 PosttranslationalModification group BEFREE DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects. 26149086 2017
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 AlteredExpression group BEFREE GABRB3, RELN, and HTR2A showed reduced expression, whereas CD38, ITGB3, MAOA, MECP2, OXTR, and PTEN showed elevated expression in autism. 22030357 2012
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 GeneticVariation group BEFREE 5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder. 20471101 2010
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 AlteredExpression group BEFREE Platelet and intestinal 5-HT2A receptor mRNA in autistic spectrum disorders - results of a pilot study. 20628446 2010
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 Biomarker group BEFREE The global chi(2) test for haplotype transmission revealed a significant association between HTR2A and autism. 17280648 2007
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 GeneticVariation group LHGDN Haplotype analysis and global chi (2) test for haplotype transmission revealed a significant association between some SNPs of HTR2A and autism. 17280648 2007
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 Biomarker group CTD_human The global chi(2) test for haplotype transmission revealed a significant association between HTR2A and autism. 17280648 2007
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 Biomarker group BEFREE Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autism. 11920848 2002
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 GeneticVariation group BEFREE No differences in allele and genotype frequencies for the 5-HT2A receptor marker were found in this autistic population compared with age-matched healthy students. 8953659 1997
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.380 Biomarker group BEFREE We examined platelet serotonin2 [5-hydroxytryptamine2 (5-HT2)] receptor binding sites, whole blood serotonin (5-HT), and plasma norepinephrine (NE) in male autistic children and their first-degree relatives. 1912104 1991