Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Nominal associations that did not survive correction for multiple testing were observed for NPSR1 rs324891 (T allele: OR=1.22, 95% CI: 1.07-1.38, P=0.002), TPH1 rs1800532 (AA genotype: OR=1.46, 95% CI: 1.14-1.89, P=0.003) and HTR2A rs6313 (T allele: OR=1.19, 95% CI: 1.07-1.33, P=0.002) in studies with samples of European ancestry and for MAOA-uVNTR in female PD (low-active alleles: OR=1.21, 95% CI: 1.07-1.38, P=0.004).
|
26390831 |
2016 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the genotype distribution of the COMT val158met and 5HTR2A 102T/C polymorphisms in PD.
|
22036916 |
2012 |
Panic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study is to evaluate the association between HTR1A, HTR2A and the 5-HTTLPR in panic disorder (PD) patients and controls.
|
20817074 |
2010 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This result suggests that 5HTR2A 1438A/G and 102T/C polymorphic regions can be associated with the phenotype or the pathogenesis of panic disorder.
|
18436425 |
2008 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
This result suggests that 5HTR2A 1438A/G and 102T/C polymorphic regions can be associated with the phenotype or the pathogenesis of panic disorder.
|
18436425 |
2008 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Nine gene-candidates, including 5-HTTLPR, MAO-A VNTR, TPH2 rs1386494, 5-HTR1A -1019C-G, 5-HTR2A 102T-C, CCKR1 246G-A, CCKR2 -215C-A, DRD1 -94G-A and COMT Val158Met, were selected for genotyping based on previous positive findings from genetic association studies in PD.
|
18832011 |
2008 |
Panic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here we report the results from an association candidate-gene approach, where we analyzed 15 single nucleotide polymorphisms (SNPs) within the gene coding for the serotonin-receptor 2A (HTR2A) in patients suffering from PD and a control sample.
|
17440930 |
2007 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Haplotype analysis supported an association of the cholecystokinin gene TG haplotype with the PD-all group (P = 0.04), whereas DRD1 receptor CAA and HTR2A receptor AT haplotypes were associated with a lower risk for PD-pure phenotype (P = 0.03 and P = 0.04, respectively).
|
15722953 |
2005 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No significant transmission disequilibrium was observed between the alleles of the T102C 5-HT2A receptor gene polymorphism and panic disorder, nor was a significant excess of either allele found in the case control analysis.
|
15182959 |
2004 |
Panic Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The study showed a positive association between panic disorder and the HTR2A gene, suggesting that HTR2A plays an important role in the pathogenesis of panic disorder.
|
12759158 |
2003 |
Panic Disorder
|
0.100 |
Biomarker
|
disease |
LHGDN |
The study showed a positive association between panic disorder and the HTR2A gene, suggesting that HTR2A plays an important role in the pathogenesis of panic disorder.
|
12759158 |
2003 |
Panic Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The authors tested for association of the 5-HT2A receptor polymorphism (T102C) and the intron 7 tryptophan hydroxylase (TPH) polymorphism (A218C) among 176 alcohol dependent patients, 35 patients with panic disorder, 50 patients with generalized anxiety disorder, 55 patients with narcolepsy and 87 healthy controls.3.
|
11444684 |
2001 |