|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
A preliminary association study between serotonin transporter (5-HTTLPR), receptor polymorphisms (5-HTR1A, 5-HTR2A) and depression symptom-clusters in a north Indian population suffering from Major Depressive Disorder (MDD).
|
31228794 |
2019 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
However, no significant associations were observed between 5-HT2A and SERT gene polymorphisms and depressive symptoms in this study group.
|
25486590 |
2015 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Our findings suggest that the HTR2A functional rs6311 polymorphism, which other studies have associated with differential HTR2A mRNA expression, may modulate the severity of depression symptoms in children with autism spectrum disorder.
|
24968012 |
2014 |
|
Depressive Symptoms
|
0.100 |
PosttranslationalModification
|
phenotype |
BEFREE |
Moreover, mean HTR2A gene methylation at baseline significantly predicted the decrease in depressive symptoms after the weight loss treatment.
|
24959950 |
2014 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The most replicated findings are the associations between rs6295 (HTR1A gene) G allele or G/G genotype and rs6311 (HTR2A gene) A allele or A/A genotype and MD or depressive symptoms.
|
23547754 |
2013 |
|
Depressive Symptoms
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Response and remission of depressive symptoms after 5 weeks of antidepressant treatment were tested against 82 GRIK4 and 37 HTR2A SNPs.
|
19924111 |
2010 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Individuals carrying the T/T or T/C genotype of the T102C polymorphism of the HTR2A gene were responsive to the protective aspects of nurturing mothering, so that in the presence of high maternal nurturance, they expressed low levels of depressive symptoms, while this was not true with the carriers of the C/C genotype.
|
17339524 |
2007 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Prediction of psychosis onset in Alzheimer disease: the role of depression symptom severity and the HTR2A T102C polymorphism.
|
17525976 |
2007 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Here we examined the interaction effect between urban/rural residency and the serotonin receptor 2A (HTR2A) gene on subclinical depressive symptoms.
|
17510953 |
2007 |
|
Depressive Symptoms
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
This study suggests a mechanism for the generation of different neuropsychiatric symptoms in AD from a single nucleotide polymorphism with reduced receptor binding in T102C 5-HT2A receptor gene homozygotes correlating with susceptibility to depressive symptoms, whereas the relative preservation of receptor binding in heterozygotes with AD correlating with susceptibility to hallucinations.
|
17481814 |
2007 |
|
Depressive Symptoms
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Brain imaging studies using positron emission tomography and single photon emission computed tomography have shown that reduction in brain 5-hydroxytryptamine type 2 (5-HT(2)) receptors may be associated with prevention of or relief from depressive symptoms.
|
15948763 |
2005 |
|
Depressive Symptoms
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
These findings explain, for example, the efficacy of estrogen therapy or 5-HT uptake blockers such as fluoxetine in treating the depressive symptoms of the premenstrual syndrome. and suggest that the sex differences in schizophrenia may also be due to an action of estrogen mediated by way of 5-HT2A receptors.3.
|
8818400 |
1996 |