HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 AlteredExpression disease BEFREE HTR2A mRNA and protein expression in human neuroblastoma SK-N-SH cells was confirmed. 23380172 2013
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 AlteredExpression disease BEFREE The goal of the present study was to determine the effects of clozapine (Cloz) and its metabolites norclozapine (Norcloz) and clozapine-N-oxide (Cloz-N-oxide) on the 5-HT(2) receptor system on the levels of protein and gene expression in in vitro systems of primary cortical cells of the rat and human hippocampal SHS5Y5 neuroblastoma cells. 14751426 2004
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 Biomarker disease BEFREE Stable transfection of the human neuroblastoma cell line SH-SY5Y with the human 5-hydroxytryptamine2A (5-HT2A) or 5-HT2C receptor cDNA produced cell lines demonstrating ligand affinities that correlated closely with those for the corresponding endogenous receptors in human frontal cortex and choroid plexus, respectively. 8931486 1996