|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In this study, we conducted a meta-analysis of the association between 5-HTR1B, 5-HTR2A, and 5-HTR2C genetic variants and ADHD.
|
30074224 |
2018 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
SNAP-25 (rs3746544) polymorphism was associated with loading for ADHD, while 5-HT2A (rs6311) and NET1 (rs2242447) polymorphisms were associated with ADHD.
|
23872233 |
2013 |
|
Attention deficit hyperactivity disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
To date, these studies have reported substantial evidence implicating several genes (dopaminergic: DRD4, DAT1, DRD5, COMT; noradrenergic: DBH, ADRA2A; serotonergic: 5-HTT, HTR1B, HTR2A; cholinergic: CHRNA4, and central nervous system development pathway: SNAP25, BDNF) in the etiology of ADHD.
|
22825876 |
2012 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No evidences for biased transmissions of both HTR2A -1438 A > G and SLC6A4 polymorphisms to ADHD youths were observed.
|
16958038 |
2007 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate seven genetic variants in three genes (serotonin transporter (5-HTT), serotonin receptor 1B (5-HTR1B) and serotonin receptor 2A (5-HTR2A)), which have previously been shown to be associated with ADHD.
|
17093889 |
2007 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The current study examined the association between adolescent outcome in ADHD and serotonin system genes, including the -1438A>G polymorphism of the serotonin 2A receptor gene (HTR2A) and the -759C>T polymorphism of the serotonin 2C receptor gene (HTR2C).
|
16741915 |
2006 |
|
Attention deficit hyperactivity disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The current study examined five variants in three serotonin genes [those that code for serotonin receptors 2A (HTR2A), 5A (HTR5A) and 6 (HTR6)] in a relatively large sample of ADHD nuclear families.
|
16701945 |
2006 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Meta-analyses of pooled ORs support association of schizophrenia to the Ser311Cys polymorphism in DRD2 and the T102C polymorphism in HTR2A, and of attention deficit hyperactivity disorder to the 48-bp repeat in DRD4.
|
15802092 |
2005 |
|
Attention deficit hyperactivity disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Over the last decade the gene encoding 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) has been implicated as a functional candidate in many neuropsychiatric phenotypes including: schizophrenia, attention deficit hyperactivity disorder (ADHD), affective disorders, eating disorders, anxiety disorders, obsessive-compulsive disorder, suicide and Alzheimer's disease (AD).
|
16026119 |
2005 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Overall, our results suggest that the investigated 5-HT2A polymorphisms are not major susceptibility factors in the etiology of ADHD.
|
12606840 |
2003 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The current study investigated whether variation in HTR2A was associated with symptoms of childhood ADHD in adult women with SAD.
|
12167522 |
2002 |
|
Attention deficit hyperactivity disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated polymorphisms in HTR(1B) and HTR(2A) (which encode the serotonin receptors 5-HT(1B) and 5-HT(2A) respectively) in a European ADHD sample.
|
12192616 |
2002 |
|
Attention deficit hyperactivity disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
One hundred and fifteen families with a total of 143 children diagnosed with ADHD (DSM-IV) were genotyped for the His452 Tyr and the T102C polymorphisms in the serotonin HTR2A receptor gene.
|
11032388 |
2000 |