Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Individuals identified at metabolic risk should undergo 10-year global risk assessment for ASCVD or coronary heart disease to determine targets of therapy for reduction of apolipoprotein B-containing lipoproteins.
|
31365087 |
2019 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein B correlates with intra-plaque necrotic core volume in stable coronary artery disease.
|
30779793 |
2019 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease.
|
30939045 |
2019 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
We aimed to investigate the kinetics of Lp(a) and LDL apolipoprotein B-100 (apoB) particles in patients with elevated Lp(a) and coronary artery disease undergoing regular apheresis.
|
30447089 |
2019 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Further, in 108,602 individuals from the Copenhagen General Population Study in random nonfasting samples, the highest versus the lowest quartile of triglycerides, total cholesterol, LDL cholesterol, remnant cholesterol, non-HDL cholesterol, lipoprotein(a), and apolipoprotein B were all associated with higher risk of both ischaemic heart disease and myocardial infarction.
|
30522787 |
2019 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Lipoprotein(a) and the Apolipoprotein B/A1 Ratio Independently Associate With Surgery for Aortic Stenosis Only in Patients With Concomitant Coronary Artery Disease.
|
29246959 |
2017 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Postprandial triglycerides, TG-rich lipoprotein triglycerides, retinyl palmitate and apolipoprotein B48 to B100 ratio were measured before (following a 12-hour fasting period) and after a fat-tolerance test meal in a middle-aged, biracial subcohort without CVD (coronary heart disease (CHD) or stroke) from the community-based Atherosclerosis Risk in Communities (ARIC) Study in 1990-1993.
|
28191321 |
2017 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Serum triglyceride, high-density lipoprotein cholesterol, apolipoprotein B, and coronary heart disease in a Chinese population undergoing coronary angiography.
|
28506386 |
2017 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Our equation to predict apoB levels showed MCVE risk prediction comparable to directly-measured apoB in high risk patients with previous coronary heart disease.
|
28830468 |
2017 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Association between apolipoprotein B EcoRI polymorphisms and coronary heart disease : A meta-analysis.
|
27637205 |
2016 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Effect of SORT1, APOB and APOE polymorphisms on LDL-C and coronary heart disease in Pakistani subjects and their comparison with Northwick Park Heart Study II.
|
27112212 |
2016 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Association Between Apolipoprotein B XbaI Polymorphism and Coronary Heart Disease in Han Chinese Population: A Meta-Analysis.
|
27172140 |
2016 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms in the apolipoprotein B (apoB) gene have been reported to be associated with coronary heart disease (CHD).
|
26537298 |
2015 |
Coronary Arteriosclerosis
|
0.200 |
Biomarker
|
disease |
BEFREE |
Recent evidence indicates that PCSK9 also modulates the metabolism of triglyceride-rich apolipoprotein B (apoB) lipoproteins, another important coronary heart disease risk factor.
|
25070550 |
2014 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
The plasma level of apolipoprotein B (apoB) is among the strongest risk factors for coronary artery disease.
|
24201112 |
2013 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.
|
23171143 |
2013 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Association between the Xba I polymorphism of APOB gene and plasma lipid level in Mexican patients with coronary artery disease.
|
22507620 |
2012 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Familial Hypercholesterolaemia (FH) is an autosomal dominant disease, caused by mutations in LDLR, APOB or PCSK9, which results in high levels of LDL-cholesterol (LDL-C) leading to early coronary heart disease.
|
23054246 |
2012 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Familial hypercholesterolemia (FH), a major risk for coronary heart disease, is predominantly associated with mutations in the genes encoding the low-density lipoprotein receptor (LDLR) and its ligand apolipoprotein B (APOB).
|
22698793 |
2012 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Another form of autosomal dominant hypercholesterolemia, familial defective apolipoprotein B-100, a genocopy of FH caused by defects in the APOB gene that lead to decreased clearance of LDL, is now established as a significant cause of coronary heart disease.
|
21657943 |
2011 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Integrated role of two apoliprotein E polymorphisms on apolipoprotein B levels and coronary artery disease in a biethnic population.
|
20715976 |
2010 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Autosomal dominant hypercholesterolemia (ADH), a major risk for coronary heart disease, is associated with mutations in the genes encoding the low-density lipoproteins receptor (LDLR), its ligand apolipoprotein B (APOB) or PCSK9 (Proprotein Convertase Subtilin Kexin 9).
|
19319977 |
2009 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
5' ins/del and 3' VNTR polymorphisms in the apolipoprotein B gene in relation to lipids and coronary artery disease.
|
18254714 |
2008 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Apolipoprotein B gene 3'VNTR polymorphism: association with plasma lipids and coronary heart disease in Han Chinese.
|
17032131 |
2006 |
Coronary Arteriosclerosis
|
0.200 |
GeneticVariation
|
disease |
BEFREE |
Genetic variations of the apolipoprotein B gene in Turkish patients with coronary artery disease.
|
16316917 |
2006 |