Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Data on the efficacy of intercellular adhesion molecule-1 antisense oligonucleotide alicaforsen in ulcerative colitis (UC) is inconsistent.
|
29207381 |
2018 |
Ulcerative Colitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
H&E staining, SEM, and VG staining showed that Garidisan repaired damaged intestinal mucosa and significantly reduced expression of ICAM-1 and CD105 in regenerated tissues of UC rats.
|
28928792 |
2017 |
Ulcerative Colitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis demonstrates that the ICAM-1 K469E polymorphism may be associated with susceptibility to CD in Europeans, but no association was found between ICAM-1 K469E and UC.
|
25942347 |
2015 |
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Although such interactions may aid in clearance of invading microorganisms by promoting PMN recruitment, engagement of ICAM-1 under pathologic conditions would increase accumulation of epithelial-associated PMN, thus contributing to mucosal injury as observed in conditions, including ulcerative colitis.
|
24345805 |
2014 |
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
RGD |
We found an increase in the levels of inflammatory markers from serum (tumor necrosis factor-α, IL-1β, IL-6 and the acute phase protein C-reactive protein) and substantia nigra (tumor necrosis factor-α, IL-1β, IL-6, inducible nitric oxide synthase, intercellular adhesion molecule-1, microglial and astroglial populations) of rats with UC, as well as an alteration of the blood-brain barrier permeability and the loss of dopaminergic neurons.
|
20584104 |
2010 |
Ulcerative Colitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Down-regulation of protein and mRNA expression of IL-8 and ICAM-1 in colon tissue of ulcerative colitis patients by partition-herb moxibustion.
|
19083096 |
2009 |
Ulcerative Colitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to assess the ICAM-1 expression in human colonic tissue representing UC, Crohn's disease (CD), adenomas, and adenocarcinomas, with special attention to the epithelium.
|
16497620 |
2006 |
Ulcerative Colitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
These findings suggest that the polymorphisms observed in the NOD2/CARD15, NOD1/CARD4, and ICAM-1 genes are not genetic susceptibility factors for Crohn's disease or ulcerative colitis in Turkey.
|
16741608 |
2006 |
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
LHGDN |
This review discusses the results from studies on the expression of ICAM-1 in colonic tissue from patients with UC.
|
16158332 |
2005 |
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
LHGDN |
Increased adhesiveness of circulating leukocytes seems to be involved in the pathogenesis of UC, and ICAM-1 is suggested to be a part of this phenomenon.
|
15550998 |
2004 |
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
CTD_human |
The results showed that NF-kappaB DNA binding activity, mRNA and protein expression of ICAM-1 and VCAM-1 were increased significantly in patients with UC, compared with normal control (P<0.05).
|
15553846 |
2004 |
Ulcerative Colitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Two candidate genes (DDXL and ICAM-1) within the IBD6 locus were examined in a case/control study with a total of 228 CD and 243 ulcerative colitis (UC) patients and 407 healthy controls.
|
15290909 |
2004 |
Ulcerative Colitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Ulcerative colitis and Crohn's disease are associated with polymorphisms of the ICAM-1 gene, which might therefore represent a functional candidate gene.
|
11726228 |
2001 |
Ulcerative Colitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Because the codon 241 polymorphism is in a functionally important domain III of ICAM-1, we may have identified an actual responsible genetic variation for genetically heterogeneous subsets of both UC and CD.
|
7615193 |
1995 |