ICAM1, intercellular adhesion molecule 1, 3383

N. diseases: 737; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.340 Biomarker group BEFREE Here, we implemented a novel chemoresistant prostate cancer patient-derived xenograft (PDX) model in NOD/SCID mice and identified CD54 as a candidate gene among the most highly enriched gene expression profiles in prostate tumors exposed to chronic cisplatin administration. 28042317 2017
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.340 Biomarker group BEFREE E2F1 knockdown inhibited prostate tumor growth in vitro and in vivo through sensitizing tumor cells to ICAM-1 mediated anti-immunity by NF-κB modulation, highlighting the potential of E2F1 as a therapeutic target. 24742333 2014
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.340 Biomarker group BEFREE Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis. 23559257 2013
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.340 GeneticVariation group LHGDN ICAM gene cluster SNPs and prostate cancer risk in African Americans. 16733712 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.340 Biomarker group CTD_human Diverse effects of zinc on NF-kappaB and AP-1 transcription factors: implications for prostate cancer progression. 16606632 2006