ICAM1, intercellular adhesion molecule 1, 3383

N. diseases: 737; N. variants: 18
Disease: Leukostasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282548
Disease: Leukostasis
Leukostasis 		0.340 AlteredExpression disease BEFREE Curcumolide alleviated retinal vascular permeability and leukostasis and attenuated the overexpression of TNF-α and ICAM-1 in diabetic retinas. 28274631 2017
CUI: C0282548
Disease: Leukostasis
Leukostasis 		0.340 AlteredExpression disease BEFREE A further study revealed hypoxic trophoblast HMGB1-induced cytotoxicity and leukostasis of HUVEC as well as higher expression of cell adhesion molecules (VCAM-1 and ICAM-1) could be reversed by pretreatment with STS. 28294475 2017
CUI: C0282548
Disease: Leukostasis
Leukostasis 		0.340 GeneticVariation disease BEFREE During diabetes, mice with CD40 expressed in Müller cells upregulated retinal tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1β), intracellular adhesion molecule 1 (ICAM-1), and nitric oxide synthase (NOS2), developed leukostasis and capillary degeneration. 27474370 2017
CUI: C0282548
Disease: Leukostasis
Leukostasis 		0.340 AlteredExpression disease BEFREE The aim of this study was to determine whether leukostasis is present in the retina, to evaluate the levels of pigment epithelium-derived factor (PEDF) and intracellular adhesion molecule-1 (ICAM-1) levels in the blood of SDT rats, and to examine the effects of PEDF on leukostasis. 17653050 2007
CUI: C0282548
Disease: Leukostasis
Leukostasis 		0.340 Biomarker disease CTD_human ICAM-1 blockade with a mAb prevents diabetic retinal leukostasis and vascular leakage by 48.5% and 85.6%, respectively. 10485912 1999