|
Asthma
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Actions on ICAM1 provide a mechanism for the locus to confer susceptibility to HRV-induced asthma.
|
30339462 |
2019 |
|
Asthma
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Peripheral blood from adults with COPD (n=17), asthma (n=20), and healthy participants (n=19) was examined for expression of CD16, CD62L, CD11b, CD11c, and CD54, and analyzed by flow cytometry.
|
31814717 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
ICAM-1 levels of T2DM groups were lower than in controls, while GPx activity, •NO, and TNF-α levels were similar among all groups.
|
31042755 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
According to the results, cinnamon supplementation has no beneficial effect on the reduction of ICAM-1 and VCAM-1 levels in patients with type 2 diabetes, which have a role in the development of atherogenesis.
|
31659242 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Receiver operating characteristic curve (ROC) analysis revealed that, the power of ICAM-1 expression levels was higher than serum ICAM-1 in diagnosis of PCOS and in differentiating T2DM from IGT and NGT subgroups.
|
31629408 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The uncontrolled BP type 2 diabetes group had significantly higher serum ICAM-1 and VCAM-1 levels compared to controlled BP type 2 diabetes and control groups.
|
30716657 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
BEFREE |
Prospective studies, investigating the association of circulating (plasma/serum) CAMs, such as intercellular adhesion molecule-1 (ICAM-1), E-selectin, vascular cell adhesion molecule-1 (VCAM-1), and P-selectin, with risk of type 2 diabetes, were included.
|
31280040 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Mechanistically, the expression of ICAM-1 in fibroblast-like synoviocytes can be triggered by glucose and interleukin-1β, which are the two important factors within the joint of T2DM.
|
30887556 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
RNA sequencing analysis conducted on samples from this group revealed that ICAM1, encoding the endothelial adhesion protein, was differentially expressed in fibroblasts from individuals with poorly controlled vs well-controlled type 2 diabetes and its levels correlated with cellular period length.
|
31134308 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The ICAM1 rs5498 might be a susceptible factor for T2D, but not T1D.
|
30798334 |
2019 |
|
Diabetic Retinopathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The results of this current meta-analysis indicated that the increased level of ICAM-1 generally exists in the patients with DR and it may associated with the severity of DR.
|
31109934 |
2019 |
|
Diabetic Retinopathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The downstream exacerbating factors including vascular endothelial growth factor (VEGF), intercellular adhesion molecule 1 (ICAM-1) and matrix metalloproteinase 2 (MMP2), which are implicated in the pathogenesis of DR and closely related to oxidative stress were also analyzed.
|
30662833 |
2019 |
|
Malaria
|
0.600 |
Biomarker
|
disease |
BEFREE |
Collectively, our results suggest that arsenic may increase host susceptibility to malaria through suppression of B cell proliferation and enhancement of adhesion between iRBC and endothelium by increasing ICAM-1.
|
30593951 |
2019 |
|
Malaria
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Healthy children had higher levels of IgG specific for ICAM-1-binding DBLβ domains from group A than from groups B and C. However, the opposite pattern was found in children with malaria, particularly among young patients.
|
31308082 |
2019 |
|
Ulcerative Colitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Data on the efficacy of intercellular adhesion molecule-1 antisense oligonucleotide alicaforsen in ulcerative colitis (UC) is inconsistent.
|
29207381 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
BEFREE |
Safety and efficacy of Melissa officinalis (lemon balm) on ApoA-I, Apo B, lipid ratio and ICAM-1 in type 2 diabetes patients: A randomized, double-blinded clinical trial.
|
30219475 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association between diabetic retinopathy in type 2 diabetes and the ICAM-1 rs5498 polymorphism: a meta-analysis of case-control studies.
|
30419874 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
BEFREE |
Paraoxonase 1 (PON1) and soluble intercellular adhesion molecule-1(sICAM-1) are intricately involved in metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) pathophysiology.
|
30327716 |
2018 |
|
Diabetic Retinopathy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association between diabetic retinopathy in type 2 diabetes and the ICAM-1 rs5498 polymorphism: a meta-analysis of case-control studies.
|
30419874 |
2018 |
|
Malaria
|
0.600 |
Biomarker
|
disease |
BEFREE |
Antibodies to Intercellular Adhesion Molecule 1-Binding Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLβ Are Biomarkers of Protective Immunity to Malaria in a Cohort of Young Children from Papua New Guinea.
|
29784862 |
2018 |
|
Ulcerative Colitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
H&E staining, SEM, and VG staining showed that Garidisan repaired damaged intestinal mucosa and significantly reduced expression of ICAM-1 and CD105 in regenerated tissues of UC rats.
|
28928792 |
2017 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The mRNA expression of JAK2, STAT3, VEGF and FLT1 and the protein levels of ICAM-1, p-JAK2, p-STAT3, SOCS1 and SOCS3 were significantly higher in the T2DM and DV groups than in the control group and in the AG490-treated groups than in the untreated groups.
|
29228585 |
2017 |
|
Diabetic Retinopathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
In conclusion, treatment with Niaspan significantly improved clinical and histopathological outcomes; decreased the expression levels of TNF‑α, NF‑κB, iNOS and ICAM‑1; and decreased apoptosis and BRB breakdown, as compared with in the retinas of DR rats.
|
28138697 |
2017 |
|
Diabetic Retinopathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Intracellular adhesion molecule 1 (ICAM-1) is an important inflammatory factor that causes retinal damage during diabetic retinopathy.
|
28104396 |
2017 |
|
Diabetic Retinopathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Inhibition or knock down of endothelial 12/15-LO in HRECs blocked HG-induced expression of ICAM-1, a well-known identified important molecule for leukocyte adhesion in DR.
|
28351645 |
2017 |