RAB7B, RAB7B, member RAS oncogene family, 338382

N. diseases: 65; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.020 Biomarker disease BEFREE Impaired autophagic flux is due to the block of autophagosome-lysosome fusion through the defective localization and function of Rab7, whose prenylation is inhibited by iPA, resulting in a net inhibition of autophagy completion that finally leads to melanoma apoptotic cell death. 29027991 2018
CUI: C0025202
Disease: melanoma
melanoma
0.020 Biomarker disease BEFREE RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway. 24981740 2014