IDE, insulin degrading enzyme, 3416

N. diseases: 71; N. variants: 19
Disease: Impaired cognition ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 Biomarker disease BEFREE MATERIAL AND METHODS The present study explored the level IDE protein in different stages of APPswe/PS1dE9 mice and their correlations with cognitive decline. 29680859 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 GeneticVariation disease BEFREE Evidence shows that cognitive impairment is more frequent among those exposed to the C allele of the rs2209972 SNP of the insulin degrading enzyme gene. 24355596 2015
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.030 GeneticVariation disease BEFREE Results indicate that alleles of IDE contribute to variability in A beta deposition in the AD brain and suggest that this relationship may have relevance for the degree of cognitive dysfunction in AD patients. 15718037 2005