IDH1, isocitrate dehydrogenase (NADP(+)) 1, 3417

N. diseases: 399; N. variants: 10
Disease: gliosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 GeneticVariation disease BEFREE Diagnostic utility of IDH1- and p53-mutation analysis in secondary gliosarcoma. 21955926 2011
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 GeneticVariation disease BEFREE <b>Objective:</b> Gliosarcoma (GSC), a rare malignant brain tumor, is considered as a variant of isocitrate dehydrogenase 1 wild type (IDH1-WT) glioblastoma (GBM). 31829033 2019
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 GeneticVariation disease BEFREE An IDH1-mutated primary gliosarcoma: case report. 27153165 2017
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 GeneticVariation disease BEFREE We identified a subset of tumors (n = 18, 8.8% of high-grade gliomas) exhibiting moderate-to-strong immunoreactivity that enriched for the IDH-wild-type glioblastoma variants gliosarcoma (n = 10) and the newly described epithelioid glioblastoma (n = 4). 28789475 2017
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 GeneticVariation disease BEFREE A case of primary gliosarcoma with both IDH1 mutation and MGMT methylation had a focal oligodendroglial component.No IDH2 mutation was found. 22270848 2012
CUI: C0206726
Disease: gliosarcoma
gliosarcoma 		0.350 Biomarker disease ORPHANET An integrated genomic analysis of human glioblastoma multiforme. 18772396 2008