Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 GeneticVariation disease BEFREE Indeed, 1p36/19q13 has been shown successively to predict increased chemosensitivity and better prognosis, to be associated with frontal location in brain and classic oligodendroglioma morphology, to be mutually exclusive with high-level gene amplification, to be actually whole chromosome arms 1p/19q codeletion, to mediate a t(1;19)(q10;p10) and to be associated with IDH mutations. 22913971 2012
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 GeneticVariation disease BEFREE The EMP3 and MGMT promoter methylation was more frequent in OII than in GBM patients, and the IDH1 mutation was absent in GBM. 22992787 2012
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 GeneticVariation disease BEFREE We first compared tumor tissues (TT) and minimally infiltrated parenchymal tissues (MIT) of four IDH1-mutated oligodendrogliomas to verify whether proteins specific to oligodendroglioma tumor cells could be identified from one patient to another. 21898821 2011
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 GeneticVariation disease BEFREE A c.515G>T (p.R172M) mutation of the IDH2 gene was only identified in a grade II oligodendroglioma patient which was wild-type for IDH1. 21643842 2011
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 GeneticVariation disease BEFREE We recently reported that the vast majority (>90%) of low-grade diffuse gliomas (diffuse astrocytoma, oligoastrocytoma and oligodendroglioma) carry at least one of the following genetic alterations: IDH1/2 mutation, TP53 mutation or 1p/19q loss. 21470325 2011
CUI: C0280475
Disease: Childhood Oligodendroglioma
Childhood Oligodendroglioma
0.400 Biomarker disease CTD_human IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group. 20160062 2010