IDH1, isocitrate dehydrogenase (NADP(+)) 1, 3417

N. diseases: 399; N. variants: 10
Disease: mixed gliomas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 Biomarker disease CTD_human Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome. 28122345 2017
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 Biomarker disease CTD_human Integrated genomic characterization of IDH1-mutant glioma malignant progression. 26618343 2016
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 Biomarker disease CTD_human Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. 25391653 2015
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 Biomarker disease CTD_human Mutational landscape and clonal architecture in grade II and III gliomas. 25848751 2015
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 GeneticVariation disease BEFREE However, the detection of divertive tumor cell clones in morphological distinct tumor components sharing IDH1- mutations as early event may provide insight into the tumorigenesis of true mixed gliomas. 22844452 2012
CUI: C0259783
Disease: mixed gliomas
mixed gliomas 		0.310 Biomarker disease CTD_human NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. 19901110 2009