IFNA1, interferon alpha 1, 3439

N. diseases: 662; N. variants: 6
Disease: Blast Phase ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 Biomarker disease BEFREE Constitutive and IFN-induced transcript levels of IFN-dependent genes in mononuclear cells, granulocytes, monocytes, lymphocytes and CD34+ cells of chronic-phase CML and blast crisis patients were assessed by Northern blot techniques and were correlated with subsequent clinical responses to IFN therapy. 8616023 1996
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 Biomarker disease BEFREE The current case therefore indicates that alpha-IFN can reduce the proportion of Ph+ cells, but is unable to prevent blast crisis. 1551082 1992
CUI: C0005699
Disease: Blast Phase
Blast Phase 		0.030 Biomarker disease BEFREE There was no significant difference between these two groups with respect to response to IFN(s), clinical course or conversion to blast crisis, nor survival. 2056769 1991