IFNA1, interferon alpha 1, 3439

N. diseases: 662; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker disease BEFREE We investigated the effects of IFN-α on the regulation of p11, 5-HTR1b and 5-HTR4 in mice and human neuroblastoma cells (SH-sy5y). 26821757 2016
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker disease BEFREE Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus in human neuroblastoma and glioblastoma cells. 25920530 2015
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker disease BEFREE To determine if treatment with type I IFN can inhibit RABV infection, mouse neuroblastoma and baby hamster kidney cells were treated with IFN-α before being infected with lab-adapted or wt RABV. 23744308 2013
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker disease BEFREE In addition, exogenous type I IFN is partially efficient in preventing and slowing down infection in human neuroblastoma cells. 21805057 2011
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 AlteredExpression disease BEFREE HLA ABC expression on NB cells was induced after transfection with pCMV-gamma IFN at a higher level than after incubation with 1000 IU/ml of purified gamma IFN. 9081706 1997
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 AlteredExpression disease BEFREE G418-resistant cells were assayed for MHC-I, MHC-II, B7-1, and neuroblastoma-associated antigen expression, as well as for gamma-IFN levels in cell culture supernatants. 8528960 1995
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker disease BEFREE The potent effect of IFN suggests a role for these modulators in NB behaviour in vivo. 3243386 1988