APOC3, apolipoprotein C3, 345

N. diseases: 153; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3151467
Disease: Apolipoprotein C-III Deficiency
Apolipoprotein C-III Deficiency 		0.610 CausalMutation disease CLINVAR
CUI: C3151467
Disease: Apolipoprotein C-III Deficiency
Apolipoprotein C-III Deficiency 		0.610 Biomarker disease CTD_human
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.460 Biomarker disease GENOMICS_ENGLAND
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.460 Biomarker disease HPO
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.200 Biomarker disease HPO
CUI: C0542037
Disease: Hypotriglyceridemia
Hypotriglyceridemia 		0.110 Biomarker disease HPO
CUI: C0853085
Disease: Decreased LDL cholesterol concentration
Decreased LDL cholesterol concentration 		0.100 Biomarker phenotype HPO
CUI: C4015848
Disease: APOLIPOPROTEIN C-III, NONGLYCOSYLATED PHENOTYPE
APOLIPOPROTEIN C-III, NONGLYCOSYLATED PHENOTYPE 		0.100 CausalMutation phenotype CLINVAR
CUI: C4551591
Disease: Increased HDL cholesterol concentration
Increased HDL cholesterol concentration 		0.100 Biomarker phenotype HPO
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.100 AlteredExpression phenotype BEFREE Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. 2167514 1990
CUI: C2936179
Disease: Obesity, Visceral
Obesity, Visceral 		0.010 GeneticVariation phenotype BEFREE Visceral obesity modulates the impact of apolipoprotein C3 gene variants on liver fat content. 21829161 2012
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.460 GeneticVariation disease BEFREE Hypercholesterolemia is associated with the apolipoprotein C-III (APOC3) genotype in children receiving HAART: an eight-year retrospective study. 22848358 2012
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.200 GeneticVariation disease LHGDN Apolipoprotein C-III and E polymorphisms and cardiovascular syndrome, hyperlipidemia, and insulin resistance in renal transplantation. 12118856 2002
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation disease BEFREE ApoC-III gene polymorphisms and risk of coronary artery disease. 12235176 2002
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.400 GeneticVariation disease LHGDN ApoC-III gene polymorphisms and risk of coronary artery disease. 12235176 2002
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.400 GeneticVariation disease BEFREE ApoC-III gene polymorphisms and risk of coronary artery disease. 12235176 2002
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.100 GeneticVariation disease BEFREE ApoC-III gene polymorphisms and risk of coronary artery disease. 12235176 2002
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.300 AlteredExpression disease BEFREE ApoC-III levels were significantly increased in MS patients, and the probability of having MS was correlated with increasing quartiles of apoC-III levels. 14563827 2003
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.400 Biomarker group BEFREE Apolipoprotein C-III (apo C-III) is a marker of cardiovascular disease risk associated with triglyceride (TG)-rich lipoproteins. 15576429 2005
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.100 GeneticVariation group BEFREE Apolipoprotein C-III (apoC-III) gene variants, which vary by race/ethnicity, have been associated with a lipid profile that resembles PI-induced dyslipidemia. 16417409 2006
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation disease BEFREE APOC3 polymorphisms were associated with lipid parameters and coronary artery disease in several populations but not all. 17367769 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.400 GeneticVariation disease BEFREE APOC3 polymorphisms were associated with lipid parameters and coronary artery disease in several populations but not all. 17367769 2007
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.100 GeneticVariation disease BEFREE APOC3 polymorphisms were associated with lipid parameters and coronary artery disease in several populations but not all. 17367769 2007
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.100 GeneticVariation group BEFREE APOC3 polymorphisms might be associated with both dyslipidemia and lipoatrophy in HAART-treated patients. 18240956 2008
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy 		0.040 GeneticVariation disease BEFREE APOC3 polymorphisms might be associated with both dyslipidemia and lipoatrophy in HAART-treated patients. 18240956 2008