APOC3, apolipoprotein C3, 345

N. diseases: 153; N. variants: 15
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 GeneticVariation disease BEFREE By multivariable Cox analysis, concurrent fatty liver (HR 7.27, 95% confidence interval: 1.52-34.76; P = 0.013), age, cirrhosis, and APOC3 rs2854116 TC/CC genotype (HR 3.93, 95% confidence interval: 1.30-11.84; P = 0.013) were independent factors predicting HCC development. 27547913 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 GeneticVariation disease BEFREE Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C. 23808989 2013
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 Biomarker disease BEFREE The impact of the APOC3 SNPs on fatty liver is small and depends on visceral obesity. 21829161 2012
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 GeneticVariation disease BEFREE The PNPLA3, but not the APOC3 rs2854116 SNP, was associated with fatty liver but not with triglyceride levels. 22105854 2012
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.050 GeneticVariation disease BEFREE Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans. 21663607 2011