APOC3, apolipoprotein C3, 345

N. diseases: 153; N. variants: 15
Disease: lipoprotein disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596848
Disease: lipoprotein disorder
lipoprotein disorder 		0.010 Biomarker disease BEFREE In summary, hypertriglyceridemia in HuCIIITg mice appears to result primarily from decreased tissue uptake of triglyceride-rich particles from the circulation, which is most likely due to increased apo CIII and decreased apo E on VLDL particles. the HuCIIITg mouse appears to be a suitable animal model of primary familial hypertriglyceridemia, and these studies suggest a possible mechanism for this common lipoprotein disorder. 1430212 1992