IFNGR2, interferon gamma receptor 2, 3460

N. diseases: 71; N. variants: 13
Disease: Hepatitis C ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.020 GeneticVariation disease BEFREE This identification of a cluster of four IFNGR2 variants strongly associated with fibrosis progression in chronic HCV infection underlines the role of IFNgamma in the development of liver fibrosis that may pave the way for new treatments. 20587546 2010
CUI: C0019196
Disease: Hepatitis C
Hepatitis C 		0.020 AlteredExpression disease BEFREE Flow cytometric analysis revealed that HCV core up-regulated of IFN-gamma receptor 2 expression, which may be responsible for HCV core-mediated enhancement of JAK-STAT pathway under IFN-gamma stimulation. 12764155 2003