Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE We determined that in human glioma tissue, glioma cell lines, and patient-derived xenograft cell lines, treatment with TMZ enhances the expression of IGF1 receptor (IGF-1R) and IGF2 and decreases the expression of IGFBP6, which sequesters IGF2. 30231881 2018
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE Together our findings suggest that IGFBP6 might be an important regulator and prognostic factor for glioma. 27650075 2017
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE By means of polymerase chain reaction (PCR), we detected mRNA transcripts for IGFBP-1 in 42%, IGFBP-2 in 65%, IGFBP-3 in 97%, IGFBP-4 in 3%, IGFBP-5 in 74%, IGFBP-6 in 94% and IGFBP-7 in 87% of the glioma cell lines. 9454896 1998