Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE Polymerase chain reaction (PCR) analysis for rearranged immunoglobulin heavy chain (IgH) genes showed a dominant band identical in size in microdissected tumor cells of the follicle center cell and mantle cell lymphomas. 10452515 1999
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE In both cases, nucleotide sequence analysis revealed common clone-specific IgH gene rearrangements in MCL and subsequent MCL-BV. 10564390 1999
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE However, the complemented analysis using Multi-FISH and/or chromosomal whole paint enabled the characterization of complex IGH translocations in follicular lymphomas and mantle cell lymphomas and the identification of all the chromosomal partners involved in the IGH rearrangement in diffuse large B-cell lymphomas. 16101124 2005
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE It is widely acknowledged that FISH is the most consistently useful test to identify the juxtaposition of the CCND1 and IGH genes in mantle cell lymphoma and is regarded as the 'gold standard'. 16373229 2005
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE In 14 CD23 negative cases IGH/BCL1 FISH detected t(11;14) and was confirmed to be mantle cell lymphoma. 16487171 2006
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE We report a case of leukemic mantle cell lymphoma of the blastoid variant with complex chromosomal rearrangements leading to the recombination of BCL1 from 11q13 and IGH from 14q32. 16527613 2006
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE However, the complemented analysis using 24-color FISH, chromosomal whole paints, telomeric probes and locus specific identifiers enabled us to characterize complex and/or masked IGH translocations in follicular lymphomas and mantle cell lymphomas and to identify all the chromosomal partners involved in IGH rearrangements in diffuse large B-cell lymphomas. 18000389 2007
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE Five M(+), IGH(-) cases were found, including two cases of follicular lymphoma (FL), one case of diffuse large B cell lymphoma, and two cases of mantle cell lymphoma. 19329714 2009
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE A case of hairy cell leukemia with CCND1-IGH@ translocation: indolent non-nodal mantle cell lymphoma revisited. 21677543 2011
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE Cloned IGH VDJ targets as tools for personalized minimal residual disease monitoring in mature lymphoid malignancies; a feasibility study in mantle cell lymphoma by the Groupe Ouest Est d'Etude des Leucémies et Autres Maladies du Sang. 22626453 2012
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE Our data show that mantle cell lymphoma cell lines resemble the IGHV and IGLV usage of mantle cell lymphoma, and foster the hypothesis that light chain stereotypy might be under-recognized. 23245212 2013
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 Biomarker disease BEFREE In this case we present an old man with concomitant mantle cell lymphoma and large granular lymphocytic leukemia diagnosed by the morphology of the bone marrow aspiration, immunophenotyping of the peripheral blood by flow cytometry detecting the increased CD3+CD4-CD8+ cells, immunohistochemical studies of lymph node showed cyclinD1+, chromosome analysis by fluorescence in situ hybridization (FISH) showed t(11,14), positive results of IGH and TCR rearrangement studies. 26045870 2015
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE Detection of t(12;14)(p13;q32) in a patient with IGH-CCND1 negative mantle cell lymphoma resembling ultra-high risk chronic lymphocytic leukemia. 26261659 2015
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 GeneticVariation disease BEFREE Translocation t(11;14)(q13;q32) CCND1-IGH is typically associated with mantle cell lymphoma or a subset of plasma cell myeloma and is exceedingly rare in myeloid neoplasm. 27810077 2016
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.100 AlteredExpression disease BEFREE Consistently, PI3Kδ inhibitors enhanced AID expression and translocation frequency to IGH and AID off-target sites in human chronic lymphocytic leukaemia and mantle cell lymphoma cell lines, and patients treated with idelalisib, but not ibrutinib, showed increased somatic hypermutation in AID off-targets. 28199309 2017